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The authors explored the impact of inflammation, total MRI burden of cerebral small vessel disease (cSVD) & D-dimer levels on outcomes in recent small subcortical infarction (RSSI). A total of 384 RSSI cases & 189 controls were studied. D-dimer correlated with worse outcomes & more severe cSVD burden. Inflammation-related D-dimer predicted neurological outcomes in RSSI cases. D-dimer & inflammation were linked to severe total MRI burden of cSVD.

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The authors explored the impact of inflammation, total MRI burden of cerebral small vessel disease (cSVD) & D-dimer levels on outcomes in recent small subcortical infarction (RSSI). A total of 384 RSSI cases & 189 controls were studied. D-dimer correlated with worse outcomes & more severe cSVD burden. Inflammation-related D-dimer predicted neurological outcomes in RSSI cases. D-dimer & inflammation were linked to severe total MRI burden of cSVD.
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