.webp&w=384&q=75){kind=logo}
Loading, please wait...
Loading, please wait...
Salmonella remains a primary cause of zoonotic foodborne disease. This makes the search for effective Salmonella antibiotic alternatives a public health priority. Specifically, avian strains like S. Pullorum cause high mortality in chicks. Meanwhile, paratyphoid strains contaminate the human food chain. Consequently, overusing antibiotics in poultry has led to widespread multi-drug resistance. Therefore, clinicians must understand how non-drug interventions in farming impact human health.
Probiotics and phytobiotics represent promising tools to enhance immune responses. These additives successfully stabilize gut microbiota and reduce pathogen shedding. Additionally, bacteriophages are specific viruses that target pathogens while leaving beneficial flora intact. However, the efficacy of these treatments depends heavily on the timing and dosage. Notably, research indicates that combining multiple interventions creates a synergistic effect. Furthermore, nanoparticles and egg yolk immunoglobulins help manage persistent asymptomatic carriers. Such biocontrol measures effectively replace conventional antibiotics in therapeutic settings. Moreover, these strategies lower the risk of intestinal dysbiosis in the birds. Ultimately, these innovations support the global One Health initiative. In conclusion, adopting these alternatives ensures a safer food supply for everyone.
Probiotics enhance the immune response and help maintain a healthy gut microbiome, which prevents pathogenic Salmonella from colonizing the intestinal tract.
Yes, bacteriophages are highly specific to target bacteria and do not harm the bird's natural microflora or create the same resistance risks as antibiotics.
Disclaimer: This content is for informational and educational purposes only. It does not constitute professional medical or veterinary advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider or veterinarian with any questions. Refer to the latest local and national guidelines for clinical practice.
References
El-Shall NA et al. Salmonella infection in chickens: pathogen, pathogenesis, and dietary non-drug feed additives as alternatives to antibiotics - a comprehensive review. Folia Microbiol (Praha). 2026 Feb 28. doi: 10.1007/s12223-025-01403-z. PMID: 41762430.
Shil S et al. Antimicrobial Resistance in Salmonella from Indian Poultry: Trends, Challenges, and One Health Perspectives. Journal of Pure and Applied Microbiology. 2026 Feb 25.
Almayman SMS & Tech SL. Uses of Bacteriophage on Salmonella in the Poultry Industry. Journal of Posthumanism. 2025;5(8):124-158.
Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.
Open your smartphone camera to scan and install.
Learn how probiotics and bacteriophages act as Salmonella antibiotic alternatives to reduce resistance and improve food safety in the poultry industry....
6 months ago
Explore the emerging role of Brixadi, an extended-release buprenorphine injection, for managing stimulant use disorder through kappa opioid receptor antagonism and steady plasma levels.
Today
A premature neonate developed upper limb compartment syndrome after uterine rupture extruded the arm through a scar defect. Conservative management with continuous monitoring yielded complete functional recovery and normal limb growth at 10-year follow-up, highlighting non-operative safety in selected cases.
Today
Dendritic cells bridge innate and adaptive immunity in myocardial infarction. This review explores their pathological roles, circulating dynamics, novel tolerogenic interventions, and how standard cardiovascular medications modulate dendritic cells to improve post-infarction myocardial repair and patient outcomes.
Today
Endoscopic posterior cervical fusion combines minimally invasive decompression, joint preparation, and rigid screw-rod fixation for atlantoaxial pathologies. Early clinical findings demonstrate solid bony union, excellent symptom relief, and minimal soft-tissue morbidity without significant vascular compromise.
Yesterday
Atherosclerosis involves extensive glycometabolic reprogramming across immune and vascular cells. This review examines how glycolysis, the pentose phosphate pathway, and lactate-driven epigenetic shifts fuel plaque vulnerability, while highlighting novel therapeutic targets like PFKFB3 and LDHA.
Today
