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In this study, breakthrough CMV infection occurred in approximately 30.8% of patients who were receiving antiviral prophylaxis.
Delayed graft function (DGF) is a primary risk factor, increasing the hazard of infection by nearly 68%.
The median time to detection is roughly 30 days post-transplant, emphasizing the need for early vigilance.
Disclaimer: This content is for informational and educational purposes only... Refer to the latest local and national guidelines for clinical practice.
References
1. Moody K et al. Risk Factors for Breakthrough Cytomegalovirus Infections While on Prophylaxis in Kidney and Pancreas Transplant Recipients. Transpl Infect Dis. 2026 Feb 17. doi: 10.1111/tid.70184. PMID: 41700449.
2. Kalidindi RK, et al. Cytomegalovirus Infection in Renal Transplant Recipients: Incidence, Risk Factors, Clinical Profile and Outcomes. Ann Case Report. 2025; 10: 2254. doi: 10.29011/2574-7754.102254.
3. Kotton CN, et al. The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-Organ Transplantation. Transplantation. 2018;102(6):900-931.

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