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Lumbar degenerative spine disease remains one of the most common causes of functional disability and chronic low back pain worldwide. When conservative treatments fail to provide symptom relief, surgical decompression becomes the definitive standard of care. Over the past decade, endoscopic lumbar surgery has emerged as an attractive, minimally invasive alternative to traditional open or microsurgical decompression. This technique minimizes soft tissue dissection, preserves bony architecture, and accelerates immediate postoperative mobilization. However, patient-specific risk factors, especially body mass index, substantially influence surgical complexity and systemic physiological stress. Clinicians frequently encounter patients across the entire weight spectrum, ranging from severely underweight individuals to those with severe obesity. Although surgeons recognize that elevated adiposity impairs wound healing and prolongs operative time, the precise relationship between body mass index and short-term surgical outcomes has remained poorly characterized. Consequently, surgical teams require granular epidemiological data to refine risk stratification and patient counseling. Understanding these dynamic relationships allows multidisciplinary teams to select the most appropriate surgical approach while anticipating post-discharge complications. As surgical centers adopt advanced spinal endoscopy, establishing evidence-based risk baselines becomes critical for optimizing surgical safety and enhancing patient recovery pathways.
To address these critical clinical questions, investigators examined data from the American College of Surgeons National Surgical Quality Improvement Program database between 2017 and 2022. This rigorous registry captured 123,457 adult patients undergoing either endoscopic or open microsurgical lumbar decompression. Within this extensive national cohort, open surgical procedures accounted for 99.7% of all operations, while endoscopic techniques represented 0.3%. Furthermore, obesity was highly prevalent, affecting 41.4% of all surgical candidates with an overall mean body mass index of 30.8 kg/m². Because baseline demographics differed markedly between surgical cohorts, researchers conducted a meticulous 1:1 propensity score matching analysis. Specifically, the matching protocol balanced 336 endoscopic patients against 336 open surgery counterparts based on age group, sex, and functional health status. In addition, standardized mean differences confirmed exceptional balance across baseline variables. The matched endoscopic cohort demonstrated substantial immediate benefits, including a dramatically shorter hospital stay of 0.9 days compared to 2.0 days in the open group. Furthermore, endoscopic surgery involved significantly higher rates of same-day outpatient discharge. These initial findings underscore the inherent recovery advantages of ultra-minimally invasive spinal approaches, although selection bias in early adoption registries warrants careful interpretation.
Thirty-day readmission represents a major quality metric and an avoidable burden for healthcare systems. In the overall cohort, the 30-day hospital readmission rate reached 4.0%. Multivariable logistic regression revealed that body mass index strongly influences unplanned hospital readmissions. Specifically, severe obesity significantly increased the odds of readmission, exhibiting an odds ratio of 1.25 compared to normal-weight peers. Several pathological factors contribute to this heightened vulnerability in severely obese individuals. For instance, expanded adipose tissue layers impair surgical field visualization and heighten tissue trauma during retracting maneuvers. In addition, obesity-associated systemic inflammation, occult glycemic variability, and compromised microvascular perfusion impair surgical wound healing. These metabolic disruptions frequently culminate in surgical site infections, seroma formation, and persistent postoperative pain syndromes that necessitate inpatient management. Conversely, patients with normal body mass index demonstrated predictable recovery trajectories and fewer unscheduled clinical evaluations. Therefore, clinicians must recognize that elevated body mass index introduces compounding systemic risks that extend well beyond the operating room. Preoperative optimization protocols should proactively target metabolic derangements and implement vigilant surveillance during the vulnerable 30-day postoperative window to curb costly hospital readmissions effectively.
While severe obesity drove unplanned readmissions, reoperation within 30 days followed a distinct and surprising clinical pattern. Across the entire surgical population, the early reoperation rate remained low at 2.5%. However, multivariable analysis revealed that underweight patients faced the highest risk of early reoperation, displaying a notable odds ratio of 1.55. This observation highlights a frequently overlooked surgical demographic in spine practice. Clinicians often concentrate risk management efforts exclusively on obese patients, yet nutritional deficiency and sarcopenia create severe biomechanical and biological vulnerabilities. Specifically, underweight individuals frequently present with compromised bone mineral density, poor muscular support, and diminished physiological reserves. Consequently, these structural deficits may accelerate recurrent disc herniation or mechanical instability following neural decompression. Moreover, impaired collagen synthesis in malnourished patients diminishes the structural integrity of the healing annulus fibrosus. In contrast, while obese patients experience wound healing delays, their risk of immediate structural revision does not eclipse that of cachectic or frail individuals. Therefore, surgical teams must broaden their preoperative assessments beyond adiposity alone. Comprehensive screening for malnutrition, frailty, and osteopenia proves essential for preventing early structural failure and revision surgery.
To refine risk stratification further, researchers deployed machine learning models evaluated with internal cross-validation to identify critical body mass index thresholds. In open lumbar decompression, the model identified a body mass index threshold of 32.5 kg/m² for early readmission and 28.5 kg/m² for reoperation. For endoscopic procedures, candidate thresholds emerged at 39.5 kg/m² for readmission and 29.0 kg/m² for reoperation. These distinct cutoff points illustrate how endoscopic approaches potentially expand the safe surgical window for patients with higher adiposity. Because endoscopic visualization avoids large muscle retractors and deep wound cavities, morbidly obese patients experience fewer dead-space complications and lower infection rates. Nevertheless, researchers caution against overinterpreting the endoscopic thresholds. Because the endoscopic cohort included only 336 patients with low absolute event rates, these specific numeric thresholds remain exploratory and hypothesis-generating. Furthermore, significant selection bias exists in real-world practice, as surgeons typically select healthier, ambulatory candidates for newly adopted endoscopic techniques. Nonetheless, these machine learning insights provide valuable benchmarks for developing personalized risk calculators. Integrating these data points into clinical workflows empowers spine surgeons to anticipate complications accurately and tailor operative approaches to individual patient anatomy.
The intersection of body mass index and surgical technique carries immediate practical relevance for spine surgeons and multidisciplinary care teams. First, clinicians should consider endoscopic decompression as a highly viable alternative for appropriately selected patients, particularly in outpatient ambulatory surgery centers. Minimizing tissue trauma through targeted endoscopic portals markedly shortens recovery times without compromising short-term safety. Second, preoperative pathways must incorporate tailored nutritional assessments for individuals at both ends of the body mass index spectrum. Severely obese candidates require strict perioperative glycemic control, subcutaneous wound care protocols, and structured early ambulation regimens to minimize readmissions. Simultaneously, underweight patients require pre-habilitation programs, dietary protein supplementation, and bone quality evaluations to reduce mechanical failure and revision surgery risks. Third, surgical practices should develop robust post-discharge monitoring systems. Remote patient monitoring, telephone check-ins, and early wound assessments can detect complications before they escalate into emergency department visits or unplanned hospitalizations. Ultimately, incorporating these risk factors into preoperative shared decision-making aligns patient expectations and enhances surgical quality. As spinal endoscopy gains wider global adoption, ongoing prospective multicenter registries will further clarify optimal patient selection criteria.
Severe obesity increases 30-day readmission risk by approximately twenty-five percent. Expanded soft tissue layers complicate surgical access, increase dead space, and elevate wound complications such as seromas and surgical site infections. Additionally, systemic inflammation and metabolic comorbidities delay tissue repair, frequently prompting unscheduled medical evaluations and hospital readmissions.
Underweight patients frequently suffer from nutritional deficiencies, sarcopenia, and poor bone mineral density. These systemic vulnerabilities compromise the structural integrity of spinal tissues, impair annular healing, and destabilize spinal biomechanics. Consequently, cachectic patients experience higher rates of recurrent disc herniation and mechanical failure, increasing the likelihood of early revision surgery.
Endoscopic lumbar surgery significantly reduces paraspinal muscle trauma, blood loss, and postoperative pain. Nationwide registry data demonstrate that endoscopic procedures result in substantially shorter hospital stays and higher rates of same-day outpatient discharge. These benefits facilitate rapid functional recovery while maintaining safety profiles comparable to open microsurgical decompression.
Disclaimer: This content is for informational and educational purposes only... Refer to the latest local and national guidelines for clinical practice.
References
Ghaith AK et al. The impact of body mass index on early readmission and reoperation following endoscopic vs. open/microsurgical lumbar surgery: A nationwide analysis. Clin Neurol Neurosurg. 2026 Oct. doi: 10.1016/j.clineuro.2026.109553. PMID: 42419172.
Ahn Y. Endoscopic spine surgery: New horizons and future trends. Korean J Spine. 2014;11(2):68-73. doi: 10.14245/kjs.2014.11.2.68.
Goyal A, Elminawy M, Kerezoudis P, et al. Impact of obesity on outcomes following lumbar spine surgery: A systematic review and meta-analysis. World Neurosurg. 2019;129:e88-e100. doi: 10.1016/j.wneu.2019.05.023.

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