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This systematic review of 17 studies (n= 1,209) evaluated the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in pediatric patients with type 1 diabetes (T1D). uNGAL levels were significantly higher in diabetes patients than in healthy controls and showed a moderate correlation with albumin-to-creatinine ratio. With high diagnostic accuracy, uNGAL may serve as an early biomarker for diabetic kidney disease (DKD).

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This systematic review of 17 studies (n= 1,209) evaluated the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in pediatric patients with type 1 diabetes (T1D). uNGAL levels were significantly higher in diabetes patients than in healthy controls and showed a moderate correlation with albumin-to-creatinine ratio. With high diagnostic accuracy, uNGAL may serve as an early biomarker for diabetic kidney disease (DKD).
Today

The Central Drugs Standard Control Organisation has granted marketing authorization for Qdenga, marking India's first approved dengue vaccine. Developed by Takeda, this two-dose live-attenuated vaccine offers protection for individuals aged 4 to 60 without requiring prior serological screening.
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Johnson & Johnson announced a $5.5 billion settlement to resolve nearly 69,000 lawsuits alleging its talc-based baby powder caused ovarian cancer. This comprehensive deal covers 99.75% of active claims. Read about the legal strategy, scientific evidence on talc exposure, and clinical counseling for patients.
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Researchers at SGPGIMS Lucknow have isolated and cultured human heart valve interstitial cells from donor tissues. This milestone advances understanding of rheumatic heart disease pathways like TGF-beta/SMAD3 and ERK1/2, laying the foundation for tissue-engineered heart valves and drug testing.
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Anterior cruciate ligament reconstruction failure lacks uniform definition. A narrative review proposes an integrative framework incorporating objective and subjective instability, persistent pain, restricted motion, graft rupture, and secondary meniscal injury to standardize clinical reporting.
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Deepinder Goyal's healthtech startup Temple is raising capital at a $500 million valuation and pricing its temporal wearable at Rs 80,000. Worn on the side of the forehead, the device tracks microvascular blood flow and real-time Entropy to monitor physiological stress, metabolic expenditure, and recovery.
Today