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Experts examined 242 postoperative adult-onset craniopharyngioma (AOCP) patients. 67.4% had metabolic dysfunction-associated fatty liver disease (MAFLD), and 32.5% of those developed advanced liver fibrosis (ALF). MAFLD was strongly linked to BMI, while ALF was associated with hypertension, HbA1c, IGF-1, and hydrocortisone dose. Managing weight, glucose, and BP, along with cautious glucocorticoid use, may help reduce MAFLD and ALF risk.
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Experts examined 242 postoperative adult-onset craniopharyngioma (AOCP) patients. 67.4% had metabolic dysfunction-associated fatty liver disease (MAFLD), and 32.5% of those developed advanced liver fibrosis (ALF). MAFLD was strongly linked to BMI, while ALF was associated with hypertension, HbA1c, IGF-1, and hydrocortisone dose. Managing weight, glucose, and BP, along with cautious glucocorticoid use, may help reduce MAFLD and ALF risk.
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