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Experts analyzed 481 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to assess the relationship between the Fibrosis-4 (FIB-4) index and lower extremity arterial disease (LEAD). LEAD prevalence increased with FIB-4 levels. Higher FIB-4 levels were independently associated with LEAD. Each unit increase in FIB-4 was linked to a 66% higher likelihood of LEAD. FIB-4 may be a marker for LEAD risk in MASLD patients.
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Experts analyzed 481 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to assess the relationship between the Fibrosis-4 (FIB-4) index and lower extremity arterial disease (LEAD). LEAD prevalence increased with FIB-4 levels. Higher FIB-4 levels were independently associated with LEAD. Each unit increase in FIB-4 was linked to a 66% higher likelihood of LEAD. FIB-4 may be a marker for LEAD risk in MASLD patients.
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