
Loading, please wait...

Loading, please wait...

Experts analyzed 481 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to assess the relationship between the Fibrosis-4 (FIB-4) index and lower extremity arterial disease (LEAD). LEAD prevalence increased with FIB-4 levels. Higher FIB-4 levels were independently associated with LEAD. Each unit increase in FIB-4 was linked to a 66% higher likelihood of LEAD. FIB-4 may be a marker for LEAD risk in MASLD patients.

Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.


Experts analyzed 481 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) to assess the relationship between the Fibrosis-4 (FIB-4) index and lower extremity arterial disease (LEAD). LEAD prevalence increased with FIB-4 levels. Higher FIB-4 levels were independently associated with LEAD. Each unit increase in FIB-4 was linked to a 66% higher likelihood of LEAD. FIB-4 may be a marker for LEAD risk in MASLD patients.
2 months ago

Explore vital recurrent stroke predictors in lacunar stroke patients managed with intensive blood pressure lowering. This analysis examines trial findings from SPS3 to uncover residual vascular risks, metabolic factors, and targeted secondary prevention strategies for high-risk neurological patients.
Today

Odisha has established India's first state-level clinical protocol specifically tailored for pregnant women with sickle cell disease. Developed with NHM and UNICEF, the framework provides structured antenatal screening, crisis mitigation, standardized referral pathways, and specialized interdisciplinary care.
Today

The Directorate General of Health Services directs Indian states to halt the hazardous reuse and reprocessing of single-use medical devices. Discover regulatory implications under the Drugs and Cosmetics Act, critical infection risks, legal liabilities, and operational changes required across clinical specialties.
Today

Mitochondria-targeted nanoparticles self-assembled from EGCG and L-glutamic acid effectively restore mitochondrial homeostasis, suppress synovial inflammation, and attenuate chondrocyte senescence in osteoarthritis, offering a promising disease-modifying nanotherapy.
Today

India is advancing preventive healthcare by integrating genomics, artificial intelligence, and quantum technologies. With the SANGAM programme sequencing one million Indian genomes, clinicians can unlock personalized therapies, detect cardiometabolic risks early, and curb the burden of diabetes and heart disease.
Today