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Obstructive sleep apnea (OSA) remains a major global health challenge, often remaining undiagnosed until significant complications arise. This sleep disorder causes repetitive upper airway collapse, leading to intermittent hypoxia and fragmented sleep. Research increasingly highlights the clinical connection between OSA and cardiac arrhythmias. These rhythm disturbances occur due to surges in sympathetic activity and negative intrathoracic pressure during obstructive events.
While global data is extensive, limited research explores the burden of rhythm disorders specifically among Indian OSA patients. A recent cross-sectional study conducted at a tertiary care center in Pune investigated fifty adult patients. The researchers used 24-hour Holter monitoring to capture rhythm abnormalities. The results showed that 64% of the participants were male, and a significant 72% were obese. Furthermore, the study identified sinus tachycardia in 24% of patients and atrial fibrillation in 12%.
The severity of OSA, measured by the apnea-hypopnea index (AHI), directly impacts the likelihood of developing rhythm disorders. Specifically, sinus tachycardia and atrial fibrillation were more frequent in patients with severe OSA. Consequently, healthcare providers must prioritize screening for OSA and cardiac arrhythmias in high-risk groups. Therefore, using 24-hour Holter monitoring alongside polysomnography can improve detection rates. Additionally, managing underlying factors like obesity remains crucial for reducing the overall cardiovascular burden.
The Pune study demonstrated a significant correlation between AHI scores and cardiac rhythm abnormalities. Severe OSA was present in 56% of the participants. Patients with higher AHI values showed a greater propensity for both tachyarrhythmias and bradyarrhythmias. This finding suggests that hypoxia and sympathetic overactivity drive the electrical remodeling of the heart. Clinicians should therefore integrate sleep assessments into the routine care of cardiology patients to mitigate these risks effectively.
In the Indian study population, sinus tachycardia (24%) and atrial fibrillation (12%) were the most common findings. Other disorders included sinus bradycardia and premature ventricular contractions.
A higher apnea-hypopnea index (AHI) is significantly associated with an increased risk of rhythm abnormalities. Severe OSA triggers more frequent episodes of hypoxia, leading to heart rhythm instability.
Disclaimer: This content is for informational and educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Refer to the latest local and national guidelines for clinical practice.
References
Boppana L et al. Cardiac Rhythm Disorders in Patients with Obstructive Sleep Apnea. Ann Afr Med. 2026 May 07. doi: 10.4103/aam.aam_535_25. PMID: 42100848.
Khan AF. Obstructive Sleep Apnea In An Indian Population: A Cross Sectional Study. Int J Med Students. 2023 Dec 19. doi: 10.5195/ijms.2023.2367.
Geovanini GR, Lorenzi-Filho G. Cardiac rhythm disorders in obstructive sleep apnea. J Thorac Dis. 2018 Dec;10(Suppl 34):S4221-S4230. doi: 10.21037/jtd.2018.12.63.

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