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This trial included 162 patients aged ≤21 years with Chiari I malformation and syringomyelia: 78 underwent decompression with duraplasty and 84 decompression alone. Six-month surgical complications were 14% versus 6% (P = 0.11). At 24 months, clinical improvement occurred in 58% versus 46%; mean syrinx reduction was 3.08 versus 1.22 mm; repeat decompression was required in 3% versus 14%. Quality-of-life changes were similar. Conclusion: Duraplasty showed better syrinx reduction and fewer repeat procedures, but the trial did not demonstrate a statistically significant difference in complications.
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This trial included 162 patients aged ≤21 years with Chiari I malformation and syringomyelia: 78 underwent decompression with duraplasty and 84 decompression alone. Six-month surgical complications were 14% versus 6% (P = 0.11). At 24 months, clinical improvement occurred in 58% versus 46%; mean syrinx reduction was 3.08 versus 1.22 mm; repeat decompression was required in 3% versus 14%. Quality-of-life changes were similar. Conclusion: Duraplasty showed better syrinx reduction and fewer repeat procedures, but the trial did not demonstrate a statistically significant difference in complications.
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