Endocrine transition care represents a critical clinical phase for adolescents and young adults with chronic childhood-onset conditions. Clinicians recognize that this period carries a high risk for loss to follow-up and clinical deterioration. Furthermore, experts agree that a multidisciplinary approach is essential for success. However, practitioners often lack practical guidance for managing specific medical aspects during the handover.

Identifying the Knowledge Gap

Many pediatric endocrine conditions involve complex genetic or epigenetic etiologies. Adult endocrinologists often find these specific health issues unfamiliar because they lack specialized training in pediatric domains. Consequently, the transition process frequently becomes fragmented. Therefore, this research addresses these gaps by delineating management strategies for both pediatric and adult clinicians.

Implementing Effective Endocrine Transition Care

Effective management requires a structured framework that begins early in adolescence. Additionally, the latest joint guidance emphasizes eleven critical domains, including patient empowerment and formal care coordination. Specifically, pediatricians must prepare patients for self-management, while adult providers should familiarize themselves with childhood-onset trajectories. Moreover, joint clinics and \"warm hand-offs\" can significantly reduce the risk of disengagement.

Frequently Asked Questions

When should transition planning for endocrinopathies ideally begin?

Clinicians recommend starting transition preparation in early adolescence, typically around age 12 to 14, to build self-management skills gradually.

What are the primary risks of poor endocrine transition?

The main risks include disengagement from healthcare services, poor treatment adherence, and an increased likelihood of acute medical complications or long-term organ damage.

Disclaimer: This content is for informational and educational purposes only. It does not constitute professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Refer to the latest local and national guidelines for clinical practice.

References

1. Zacharin M et al. Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies. Clin Endocrinol (Oxf). 2026 Mar 12. doi: 10.1111/cen.70118. PMID: 41820251.

2. Le Roux E et al. European Society for Paediatric Endocrinology and European Society of Endocrinology Joint Clinical Practice Guidance for Healthcare Transition from Paediatric to Adult Endocrine Care. Horm Res Paediatr. 2026 Feb 19. doi: 10.1159/000550744.