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Researchers analyzed 19,400 adults to investigate the combined impact of smoking and osteoporosis on all-cause mortality. The highest mortality rate was observed in individuals with both smoking and osteoporosis, with a 146% increased mortality risk. The overall mortality rate was 13.1%. While the relative excess risk due to interaction (RERI) was not statistically significant, the attributable proportion suggested a synergistic effect.

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Researchers analyzed 19,400 adults to investigate the combined impact of smoking and osteoporosis on all-cause mortality. The highest mortality rate was observed in individuals with both smoking and osteoporosis, with a 146% increased mortality risk. The overall mortality rate was 13.1%. While the relative excess risk due to interaction (RERI) was not statistically significant, the attributable proportion suggested a synergistic effect.
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