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Experts evaluated presurgical short-term endocrine therapy (preSTE) in 269 postmenopausal HR+ breast cancer patients. Median preSTE duration was 39 days. It significantly reduced tumor size and Ki67 expression. Patients with a preoperative endocrine prognostic index (PEPI) score ≥ 4 exhibited worse disease-free and overall survival. The study concludes that preSTE is effective, and Ki67 levels and PEPI scores are useful prognostic predictors.
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Experts evaluated presurgical short-term endocrine therapy (preSTE) in 269 postmenopausal HR+ breast cancer patients. Median preSTE duration was 39 days. It significantly reduced tumor size and Ki67 expression. Patients with a preoperative endocrine prognostic index (PEPI) score ≥ 4 exhibited worse disease-free and overall survival. The study concludes that preSTE is effective, and Ki67 levels and PEPI scores are useful prognostic predictors.
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