.webp&w=384&q=75){kind=logo}
Loading, please wait...
Loading, please wait...
This systematic review of 17 studies (n= 1,209) evaluated the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in pediatric patients with type 1 diabetes (T1D). uNGAL levels were significantly higher in diabetes patients than in healthy controls and showed a moderate correlation with albumin-to-creatinine ratio. With high diagnostic accuracy, uNGAL may serve as an early biomarker for diabetic kidney disease (DKD).
Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.
Open your smartphone camera to scan and install.
This systematic review of 17 studies (n= 1,209) evaluated the prognostic role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) in pediatric patients with type 1 diabetes (T1D). uNGAL levels were significantly higher in diabetes patients than in healthy controls and showed a moderate correlation with albumin-to-creatinine ratio. With high diagnostic accuracy, uNGAL may serve as an early biomarker for diabetic kidney disease (DKD).
last month
A breakthrough study using human colonic organoids demonstrates that bacterial serine protease EspP, an EHEC cytotoxin, halts epithelial proliferation and preferentially triggers enteroendocrine cell differentiation, promoting pro-inflammatory chemokine release and immune cell recruitment.
2 days back
Recent research reveals that downregulating YAP1/TAZ-TEAD via Hippo signaling triggers spontaneous human trophoblast syncytialization in 3D cultures, illuminating placental biology and preeclampsia.
2 days back
A landmark comparative study evaluates atrial electrophysiology across humans, swine, and rodents. By linking cellular recordings with transcriptomics and in silico modeling, researchers resolve cross-species gaps, explaining translational failures to advance targeted therapies for atrial arrhythmias.
2 days back
A novel pathology-adaptive surface engineering strategy uses functionalized plasma polymer coatings to selectively modulate AGE adsorption, reducing oxidative stress and restoring bone formation in diabetic and aging microenvironments.
4 weeks back
Researchers have developed an innovative ultrasound-responsive nano-contrast agent that co-delivers CIITA-siRNA and rapamycin directly to inflamed thyroid tissue, significantly reducing autoimmune injury and thyroid autoantibodies in preclinical models of Hashimoto thyroiditis.
2 days back
