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This national real-world study analyzed 58,050 adults with opioid (n=28,808), alcohol (n=23,281), or cannabis dependence (n=5,961). Anxiety and depression were most common in opioid dependence (14.7% and 13.5%), while depression predominated in alcohol dependence (21.8%). Men had lower adjusted odds of anxiety, bipolar, depression, and trauma-related disorders than women, but higher odds of psychotic disorders with opioid or cannabis dependence.
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This national real-world study analyzed 58,050 adults with opioid (n=28,808), alcohol (n=23,281), or cannabis dependence (n=5,961). Anxiety and depression were most common in opioid dependence (14.7% and 13.5%), while depression predominated in alcohol dependence (21.8%). Men had lower adjusted odds of anxiety, bipolar, depression, and trauma-related disorders than women, but higher odds of psychotic disorders with opioid or cannabis dependence.
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