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This study evaluated 194 patients with suspected glioma who underwent preoperative navigated transcranial magnetic stimulation (nTMS) motor mapping between 2015 and 2022. Reduced resting motor threshold ratio (OR 0.066; P=.046), increased recruitment curve slope ratio (OR 1.311; P=.028), shorter tumor-to-tract distance (OR 0.888; P=.002), and recurrent tumor status (OR 2.724; P=.017) were associated with motor deficits, highlighting nTMS markers of reduced neuronal reserve.

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This study evaluated 194 patients with suspected glioma who underwent preoperative navigated transcranial magnetic stimulation (nTMS) motor mapping between 2015 and 2022. Reduced resting motor threshold ratio (OR 0.066; P=.046), increased recruitment curve slope ratio (OR 1.311; P=.028), shorter tumor-to-tract distance (OR 0.888; P=.002), and recurrent tumor status (OR 2.724; P=.017) were associated with motor deficits, highlighting nTMS markers of reduced neuronal reserve.
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