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This study of 1109 breast cancer patients found that MRI-based Global Fractal Dimension (FD), quantifying tumor morphological complexity, independently predicted pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). A nomogram integrating Global FD with HR and HER2 status showed strong performance in predicting pCR and stratifying disease-free (DFS) and overall survival (OS).
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This study of 1109 breast cancer patients found that MRI-based Global Fractal Dimension (FD), quantifying tumor morphological complexity, independently predicted pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). A nomogram integrating Global FD with HR and HER2 status showed strong performance in predicting pCR and stratifying disease-free (DFS) and overall survival (OS).
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