.webp&w=384&q=75){kind=logo}
Loading, please wait...
Loading, please wait...
This retrospective NSQIP study evaluated 13,716 adults undergoing craniotomy for supratentorial malignant brain tumors, comparing 8,830 patients before COVID-19 (2016–2019) with 4,886 during the pandemic (2020–2021). Thirty-day mortality was 3.1% pre-pandemic versus 2.6% during COVID-19 (P=0.087). After adjustment, pandemic-period surgery was associated with lower odds of 30-day mortality (OR 0.70; 95% CI 0.55–0.88; P=0.0027). Age, disseminated cancer and postoperative pneumonia, prolonged ventilation and stroke remained significant mortality-associated factors.
Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.
Open your smartphone camera to scan and install.
This retrospective NSQIP study evaluated 13,716 adults undergoing craniotomy for supratentorial malignant brain tumors, comparing 8,830 patients before COVID-19 (2016–2019) with 4,886 during the pandemic (2020–2021). Thirty-day mortality was 3.1% pre-pandemic versus 2.6% during COVID-19 (P=0.087). After adjustment, pandemic-period surgery was associated with lower odds of 30-day mortality (OR 0.70; 95% CI 0.55–0.88; P=0.0027). Age, disseminated cancer and postoperative pneumonia, prolonged ventilation and stroke remained significant mortality-associated factors.
last month
Depemokimab offers twice-yearly dosing for severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps, significantly cutting exacerbations and hospital admissions.
Last week
A novel copper metal-organic framework hydrogel remodels the uterine microenvironment to stimulate robust endometrial regeneration, reduce intrauterine fibrosis, and restore reproductive fertility, offering a groundbreaking strategy for managing refractory endometrial damage and Asherman syndrome.
Last week
New research reveals that non-ablative radiotherapy suppresses ventricular tachycardia by increasing conduction velocity via NaV1.5 upregulation and action potential prolongation. However, sustained sodium current elevation and depressed calcium handling highlight the need for careful clinical translation.
Last week
A single-cell transcriptomic atlas reveals how peripheral nerve injuries cause dorsal root ganglion remodeling. By evaluating proximal nerve crush and resection, researchers identify distinct glial and immune programs that resolve neuropathic pain and promote regeneration.
Last week
A breakthrough study demonstrates that fullerol-primed extracellular vesicles generated in a 3D SECCS bioreactor attenuate ferroptosis and restore myogenic regeneration in diabetes via the FOXO3 pathway, offering a cell-free therapeutic strategy for diabetic musculoskeletal degeneration.
Last week
