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Experts examined 72 biopsy-proven DKD patients and found that tubular long-chain fatty acid CoA ligase 4 (ACSL4) expression was higher in DKD patients than in controls and was positively correlated with proteinuria and negatively with albumin and hemoglobin. Higher ACSL4 levels were linked to a faster decline in eGFR. ACSL4 may serve as a biomarker for identifying DKD patients at high risk of rapid kidney function decline.
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Experts examined 72 biopsy-proven DKD patients and found that tubular long-chain fatty acid CoA ligase 4 (ACSL4) expression was higher in DKD patients than in controls and was positively correlated with proteinuria and negatively with albumin and hemoglobin. Higher ACSL4 levels were linked to a faster decline in eGFR. ACSL4 may serve as a biomarker for identifying DKD patients at high risk of rapid kidney function decline.
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