
Loading, please wait...

Loading, please wait...

Experts examined 408 children with type 1 diabetes mellitus (T1DM) and found no significant secular trends in BMI at diagnosis. However, 14.46% were overweight/obese at diagnosis, and 77.97% of these remained so at follow-up. Mean BMI z-scores increased post-diagnosis, with 27.70% meeting overweight/obesity criteria. Obesity at T1DM diagnosis persists, necessitating early intervention to mitigate long-term metabolic risks.

Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.


Experts examined 408 children with type 1 diabetes mellitus (T1DM) and found no significant secular trends in BMI at diagnosis. However, 14.46% were overweight/obese at diagnosis, and 77.97% of these remained so at follow-up. Mean BMI z-scores increased post-diagnosis, with 27.70% meeting overweight/obesity criteria. Obesity at T1DM diagnosis persists, necessitating early intervention to mitigate long-term metabolic risks.
2 months ago

A retrospective cohort study of 7,716 ICU patients from the MIMIC-IV database demonstrates that Gradient Boosting Decision Trees significantly outperform traditional SOFA scores in predicting in-hospital mortality among patients with sepsis and diabetes, with SHAP analysis providing clinical interpretability.
Today

A prenatal case highlights severe glutaric acidemia type II presenting as bilateral hyperechoic cystic kidneys at 18 weeks. Whole-exome sequencing revealed a novel homozygous ETFDH frameshift variant, demonstrating the power of rapid genetic testing in fetal renal anomalies.
Today

This article reviews the forensic and clinical complexities of acute myocarditis arising on left ventricular hypertrophy in children, highlighting early diagnostic red flags and multidisciplinary postmortem autopsy protocols.
Today

This comparative study evaluates posterior labral tears with and without glenohumeral instability, highlighting distinct demographic patterns, MRI underestimation in stable shoulders, and successful arthroscopic repair outcomes.
Yesterday

A clinical study demonstrates that early intervention with tocilizumab, either as monotherapy or bridged with corticosteroids, achieves significant proptosis reduction and resolves active inflammation in treatment-naive thyroid eye disease.
Yesterday