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A study investigated the effect of melatonin on sleep disorders in children (2-12 years) with cerebral palsy (CP). Double-blind clinical trial with 2 groups (melatonin and placebo) showed melatonin effectively improved time to fall asleep and increased sleep duration in CP children. Sleep disorders are prevalent in children with CP. Melatonin is effective in improving sleep duration and onset time, emphasizing the need for timely treatment.

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A study investigated the effect of melatonin on sleep disorders in children (2-12 years) with cerebral palsy (CP). Double-blind clinical trial with 2 groups (melatonin and placebo) showed melatonin effectively improved time to fall asleep and increased sleep duration in CP children. Sleep disorders are prevalent in children with CP. Melatonin is effective in improving sleep duration and onset time, emphasizing the need for timely treatment.
2 months ago

A retrospective cohort study of 7,716 ICU patients from the MIMIC-IV database demonstrates that Gradient Boosting Decision Trees significantly outperform traditional SOFA scores in predicting in-hospital mortality among patients with sepsis and diabetes, with SHAP analysis providing clinical interpretability.
Today

Occult maternal malignancy accounts for 3.82% of persistent unreportable NIPT results with genomic noise. Multiple chromosomal aberrations, notably on chromosome 18, warrant thorough oncological evaluation and whole-body MRI to ensure timely maternal diagnosis while preserving fetal care.
Today

This article reviews the forensic and clinical complexities of acute myocarditis arising on left ventricular hypertrophy in children, highlighting early diagnostic red flags and multidisciplinary postmortem autopsy protocols.
Today

This comparative study evaluates posterior labral tears with and without glenohumeral instability, highlighting distinct demographic patterns, MRI underestimation in stable shoulders, and successful arthroscopic repair outcomes.
Yesterday

A clinical study demonstrates that early intervention with tocilizumab, either as monotherapy or bridged with corticosteroids, achieves significant proptosis reduction and resolves active inflammation in treatment-naive thyroid eye disease.
Yesterday