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This study evaluated the efficacy and safety of electroacupuncture in patients with postherpetic neuralgia (PHN), a chronic neuropathic pain condition that may persist following herpes zoster infection. The multicentre trial was conducted across seven tertiary hospitals in China and included 448 patients aged 45–75 years with moderate-to-severe PHN. Participants were randomized to receive electroacupuncture (n=225) or sham electroacupuncture (n=223). The treatment protocol consisted of 20 sessions over four weeks, followed by a four-week post-treatment observation period. The primary outcome was the change in pain intensity measured using the 11-point Numeric Rating Scale (NRS-11), with a reduction of at least 30% considered a clinically relevant response. At week 4, the mean pain score decreased by 1.52 points in the electroacupuncture group compared with 0.99 points in the sham group, demonstrating a statistically significant between-group difference of −0.53 points
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This study evaluated the efficacy and safety of electroacupuncture in patients with postherpetic neuralgia (PHN), a chronic neuropathic pain condition that may persist following herpes zoster infection. The multicentre trial was conducted across seven tertiary hospitals in China and included 448 patients aged 45–75 years with moderate-to-severe PHN. Participants were randomized to receive electroacupuncture (n=225) or sham electroacupuncture (n=223). The treatment protocol consisted of 20 sessions over four weeks, followed by a four-week post-treatment observation period. The primary outcome was the change in pain intensity measured using the 11-point Numeric Rating Scale (NRS-11), with a reduction of at least 30% considered a clinically relevant response. At week 4, the mean pain score decreased by 1.52 points in the electroacupuncture group compared with 0.99 points in the sham group, demonstrating a statistically significant between-group difference of −0.53 points
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