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Low-dose vaginal estrogen is an effective treatment for genitourinary symptoms of menopause such as vaginal dryness, dyspareunia and urinary discomfort. Because systemic exposure is much lower than with systemic hormone therapy, local treatment directly addresses estrogen-deficient vaginal and lower urinary tract tissues. For gynecologists, therapy should be matched to symptom pattern, personal history and patient preference. Women with current or previous hormone-sensitive cancer require individualized discussion with their oncology team. Symptoms commonly recur when treatment stops, so long-term management and follow-up are often needed.

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Low-dose vaginal estrogen is an effective treatment for genitourinary symptoms of menopause such as vaginal dryness, dyspareunia and urinary discomfort. Because systemic exposure is much lower than with systemic hormone therapy, local treatment directly addresses estrogen-deficient vaginal and lower urinary tract tissues. For gynecologists, therapy should be matched to symptom pattern, personal history and patient preference. Women with current or previous hormone-sensitive cancer require individualized discussion with their oncology team. Symptoms commonly recur when treatment stops, so long-term management and follow-up are often needed.
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