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This prospective randomized contralateral-eye study compared topography-guided LASIK with SMILE for myopia and myopic astigmatism. At three months, the topography-guided LASIK eyes achieved higher rates of 20/20 and 20/16 uncorrected distance vision and showed tighter refractive predictability in the study population. The authors attributed part of the difference to the ability of the LASIK platform to compensate for eye movements, cyclorotation and centration during treatment. The study demonstrates the potential value of linking corneal topography to the ablation strategy rather than treating refractive error as a purely manifest prescription. For HCPs, the findings are most useful when counselling patients about highly customised refractive correction. Topography-guided procedures remain dependent on good preoperative measurements, tear-film quality and appropriate corneal selection criteria. The results should not be interpreted as a universal verdict against SMILE, because technology continues to evolve. Instead, they show how platform-specific capabilities can influence outcomes. The evidence fits AIOC's focus on Contoura and topography-guided refractive interventions.

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This prospective randomized contralateral-eye study compared topography-guided LASIK with SMILE for myopia and myopic astigmatism. At three months, the topography-guided LASIK eyes achieved higher rates of 20/20 and 20/16 uncorrected distance vision and showed tighter refractive predictability in the study population. The authors attributed part of the difference to the ability of the LASIK platform to compensate for eye movements, cyclorotation and centration during treatment. The study demonstrates the potential value of linking corneal topography to the ablation strategy rather than treating refractive error as a purely manifest prescription. For HCPs, the findings are most useful when counselling patients about highly customised refractive correction. Topography-guided procedures remain dependent on good preoperative measurements, tear-film quality and appropriate corneal selection criteria. The results should not be interpreted as a universal verdict against SMILE, because technology continues to evolve. Instead, they show how platform-specific capabilities can influence outcomes. The evidence fits AIOC's focus on Contoura and topography-guided refractive interventions.
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