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Sentinel lymph-node mapping has emerged as an alternative to systematic lymphadenectomy for staging selected patients with apparent uterine-confined endometrial cancer. Prospective and retrospective studies show high detection rates when cervical injection and standardized surgical algorithms are used. The potential advantage is lower surgical morbidity, including reduced lymphoedema risk, while preserving staging information. For gynecologic oncologists, the technique requires adherence to an established mapping protocol and attention to side-specific assessment when mapping fails. Patient selection remains important, particularly in high-grade or advanced disease where comprehensive staging may still be required. The evidence supports sentinel mapping as a structured staging strategy rather than a simple replacement for all nodal surgery.
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Sentinel lymph-node mapping has emerged as an alternative to systematic lymphadenectomy for staging selected patients with apparent uterine-confined endometrial cancer. Prospective and retrospective studies show high detection rates when cervical injection and standardized surgical algorithms are used. The potential advantage is lower surgical morbidity, including reduced lymphoedema risk, while preserving staging information. For gynecologic oncologists, the technique requires adherence to an established mapping protocol and attention to side-specific assessment when mapping fails. Patient selection remains important, particularly in high-grade or advanced disease where comprehensive staging may still be required. The evidence supports sentinel mapping as a structured staging strategy rather than a simple replacement for all nodal surgery.
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