.webp&w=384&q=75){kind=logo}
Loading, please wait...
Loading, please wait...
Sentinel lymph-node mapping has emerged as an alternative to systematic lymphadenectomy for staging selected patients with apparent uterine-confined endometrial cancer. Prospective and retrospective studies show high detection rates when cervical injection and standardized surgical algorithms are used. The potential advantage is lower surgical morbidity, including reduced lymphoedema risk, while preserving staging information. For gynecologic oncologists, the technique requires adherence to an established mapping protocol and attention to side-specific assessment when mapping fails. Patient selection remains important, particularly in high-grade or advanced disease where comprehensive staging may still be required. The evidence supports sentinel mapping as a structured staging strategy rather than a simple replacement for all nodal surgery.
Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.
Open your smartphone camera to scan and install.
Sentinel lymph-node mapping has emerged as an alternative to systematic lymphadenectomy for staging selected patients with apparent uterine-confined endometrial cancer. Prospective and retrospective studies show high detection rates when cervical injection and standardized surgical algorithms are used. The potential advantage is lower surgical morbidity, including reduced lymphoedema risk, while preserving staging information. For gynecologic oncologists, the technique requires adherence to an established mapping protocol and attention to side-specific assessment when mapping fails. Patient selection remains important, particularly in high-grade or advanced disease where comprehensive staging may still be required. The evidence supports sentinel mapping as a structured staging strategy rather than a simple replacement for all nodal surgery.
Today
The phase 3 ACACIA-HCM trial reveals that aficamten improves cardiac structure, diastolic relaxation, functional capacity, and symptom burden in symptomatic nonobstructive hypertrophic cardiomyopathy, marking a major milestone in targeted myosin inhibition.
6 days back
A clinical study shows that automated breast ultrasound paired with artificial intelligence accurately classifies BIRADS 3-4 lesions, reaching 95% sensitivity and 79% specificity. This diagnostic advance promises to reduce unnecessary core needle biopsies and refine clinical workflows in breast imaging.
3 weeks back
Researchers have engineered freestanding hierarchical-porous BCZT thin films that resist cracking and enhance ultrasonic energy harvesting in soft tissue. Achieving high piezoelectric output and acoustic matching, this lead-free material offers transformative potential for implantable bioelectronics.
Last week
A novel pathology-adaptive surface engineering strategy uses functionalized plasma polymer coatings to selectively modulate AGE adsorption, reducing oxidative stress and restoring bone formation in diabetic and aging microenvironments.
3 weeks back
A breakthrough study identifies the Klotho/PKCα/CUX1/SPARC/TGFβ-RII axis as a critical driver of podocyte mitochondrial injury and ferroptosis in diabetic kidney disease, unveiling promising molecular targets to halt renal disease progression.
6 days back
