
Loading, please wait...

Loading, please wait...

Systematic reviews of randomized trials show that supervised pelvic-floor muscle training improves stress urinary incontinence and reduces leakage episodes in women. The intervention is low risk and can be used during pregnancy, postpartum and before or after continence surgery. For urogynecologists, technique and adherence matter; structured instruction and follow-up are more useful than a generic recommendation to exercise the pelvic floor. Training should be offered before invasive treatment when clinically appropriate, while persistent symptoms warrant reassessment and consideration of surgical or other therapies.

Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.


Systematic reviews of randomized trials show that supervised pelvic-floor muscle training improves stress urinary incontinence and reduces leakage episodes in women. The intervention is low risk and can be used during pregnancy, postpartum and before or after continence surgery. For urogynecologists, technique and adherence matter; structured instruction and follow-up are more useful than a generic recommendation to exercise the pelvic floor. Training should be offered before invasive treatment when clinically appropriate, while persistent symptoms warrant reassessment and consideration of surgical or other therapies.
4 weeks back

A bioengineered oral nanozyme microsupplement converts pathological ROS into a protective polydopamine hydrogel shield. By curbing neutrophil extracellular traps and balancing T cells, this platform outperforms standard 5-ASA in preclinical colitis models, opening new paths for sustained remission.
4 days back

Recent research reveals that downregulating YAP1/TAZ-TEAD via Hippo signaling triggers spontaneous human trophoblast syncytialization in 3D cultures, illuminating placental biology and preeclampsia.
4 weeks back

Abdominal aortic aneurysm rupture remains a catastrophic vascular emergency. Groundbreaking research reveals that USP53 accelerates aneurysm progression by reprogramming smooth muscle cell metabolism toward aerobic glycolysis, highlighting a promising target beyond conventional diameter-based surveillance.
5 days back

A breakthrough study leverages natural language processing to accurately identify incident medication-related osteonecrosis of the jaw and track antiresorptive drug holidays from clinical narratives in electronic health records, advancing osteoporosis pharmacovigilance and dental safety.
4 days back

Recent research defines ferro-aging as a conserved iron-lipid axis driving organ decline across primates. Age-related iron dyshomeostasis stimulates ACSL4-mediated lipid peroxidation, promoting cellular senescence. Notably, vitamin C directly inhibits ACSL4, suppressing phospholipid oxidation and multi-organ decay.
5 days back