
Loading, please wait...

Loading, please wait...

Severe slipped capital femoral epiphysis presents a difficult balance between correcting deformity and avoiding complications such as femoral-head avascular necrosis. This systematic review and meta-analysis compared the modified Dunn procedure with in-situ fixation in moderate and severe SCFE. The modified Dunn approach produced better radiographic correction, including improved Southwick and alpha angles, but did not demonstrate a clear clinical outcome advantage. Importantly, the pooled evidence did not show a meaningful difference in the odds of avascular necrosis or chondrolysis, although the evidence base was small and heterogeneous. The study therefore challenges the assumption that superior anatomical correction automatically results in superior patient-reported function. The authors emphasised that, when modified Dunn is used, it should be concentrated in high-volume centres with appropriate expertise because of the technical demands of the procedure. For clinicians, the practical message is to distinguish the goals of deformity correction from the goals of safe, durable function. In a severe or unstable slip, referral to an experienced paediatric hip surgeon may be more important than choosing a particular technique in isolation. The paper supports careful case selection and honest discussion of both radiographic and clinical uncertainty.

Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.


Severe slipped capital femoral epiphysis presents a difficult balance between correcting deformity and avoiding complications such as femoral-head avascular necrosis. This systematic review and meta-analysis compared the modified Dunn procedure with in-situ fixation in moderate and severe SCFE. The modified Dunn approach produced better radiographic correction, including improved Southwick and alpha angles, but did not demonstrate a clear clinical outcome advantage. Importantly, the pooled evidence did not show a meaningful difference in the odds of avascular necrosis or chondrolysis, although the evidence base was small and heterogeneous. The study therefore challenges the assumption that superior anatomical correction automatically results in superior patient-reported function. The authors emphasised that, when modified Dunn is used, it should be concentrated in high-volume centres with appropriate expertise because of the technical demands of the procedure. For clinicians, the practical message is to distinguish the goals of deformity correction from the goals of safe, durable function. In a severe or unstable slip, referral to an experienced paediatric hip surgeon may be more important than choosing a particular technique in isolation. The paper supports careful case selection and honest discussion of both radiographic and clinical uncertainty.
Today

The phase 3 ACACIA-HCM trial reveals that aficamten improves cardiac structure, diastolic relaxation, functional capacity, and symptom burden in symptomatic nonobstructive hypertrophic cardiomyopathy, marking a major milestone in targeted myosin inhibition.
6 days back

A clinical study shows that automated breast ultrasound paired with artificial intelligence accurately classifies BIRADS 3-4 lesions, reaching 95% sensitivity and 79% specificity. This diagnostic advance promises to reduce unnecessary core needle biopsies and refine clinical workflows in breast imaging.
3 weeks back

Researchers have engineered freestanding hierarchical-porous BCZT thin films that resist cracking and enhance ultrasonic energy harvesting in soft tissue. Achieving high piezoelectric output and acoustic matching, this lead-free material offers transformative potential for implantable bioelectronics.
6 days back

A novel pathology-adaptive surface engineering strategy uses functionalized plasma polymer coatings to selectively modulate AGE adsorption, reducing oxidative stress and restoring bone formation in diabetic and aging microenvironments.
3 weeks back

A breakthrough study identifies the Klotho/PKCα/CUX1/SPARC/TGFβ-RII axis as a critical driver of podocyte mitochondrial injury and ferroptosis in diabetic kidney disease, unveiling promising molecular targets to halt renal disease progression.
6 days back