
Loading, please wait...

Loading, please wait...
The HubBLe randomized trial compared haemorrhoidal artery ligation with rubber band ligation for symptomatic second- and third-degree haemorrhoids. The study is useful because both techniques are designed to avoid conventional excisional haemorrhoidectomy, yet they differ in invasiveness, recurrence profile, postoperative discomfort and resource requirements. The trial found that both approaches were effective, but they did not offer identical trade-offs. Rubber band ligation remained a simple and relatively inexpensive outpatient option, while haemorrhoidal artery ligation involved a more procedural approach with different patterns of recurrence and postoperative experience. For surgeons, the key lesson is that “less invasive” does not automatically mean “better” across every endpoint. Treatment choice should consider haemorrhoid grade, symptom pattern, patient expectations, recurrence tolerance, availability of anaesthesia and local expertise. The evidence also supports a step-up philosophy in proctology: the simplest effective intervention should often be considered first, with more invasive options reserved for patients who need them. HubBLe is particularly relevant to the ASICON proctology focus because it demonstrates how comparative trials can help surgeons choose between modern minimally invasive treatments rather than relying solely on technical preference or habit.

Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.

The HubBLe randomized trial compared haemorrhoidal artery ligation with rubber band ligation for symptomatic second- and third-degree haemorrhoids. The study is useful because both techniques are designed to avoid conventional excisional haemorrhoidectomy, yet they differ in invasiveness, recurrence profile, postoperative discomfort and resource requirements. The trial found that both approaches were effective, but they did not offer identical trade-offs. Rubber band ligation remained a simple and relatively inexpensive outpatient option, while haemorrhoidal artery ligation involved a more procedural approach with different patterns of recurrence and postoperative experience. For surgeons, the key lesson is that “less invasive” does not automatically mean “better” across every endpoint. Treatment choice should consider haemorrhoid grade, symptom pattern, patient expectations, recurrence tolerance, availability of anaesthesia and local expertise. The evidence also supports a step-up philosophy in proctology: the simplest effective intervention should often be considered first, with more invasive options reserved for patients who need them. HubBLe is particularly relevant to the ASICON proctology focus because it demonstrates how comparative trials can help surgeons choose between modern minimally invasive treatments rather than relying solely on technical preference or habit.
Yesterday

The phase 3 ACACIA-HCM trial reveals that aficamten improves cardiac structure, diastolic relaxation, functional capacity, and symptom burden in symptomatic nonobstructive hypertrophic cardiomyopathy, marking a major milestone in targeted myosin inhibition.
6 days back

A clinical study shows that automated breast ultrasound paired with artificial intelligence accurately classifies BIRADS 3-4 lesions, reaching 95% sensitivity and 79% specificity. This diagnostic advance promises to reduce unnecessary core needle biopsies and refine clinical workflows in breast imaging.
3 weeks back

Researchers have engineered freestanding hierarchical-porous BCZT thin films that resist cracking and enhance ultrasonic energy harvesting in soft tissue. Achieving high piezoelectric output and acoustic matching, this lead-free material offers transformative potential for implantable bioelectronics.
6 days back

A novel pathology-adaptive surface engineering strategy uses functionalized plasma polymer coatings to selectively modulate AGE adsorption, reducing oxidative stress and restoring bone formation in diabetic and aging microenvironments.
3 weeks back

A breakthrough study identifies the Klotho/PKCα/CUX1/SPARC/TGFβ-RII axis as a critical driver of podocyte mitochondrial injury and ferroptosis in diabetic kidney disease, unveiling promising molecular targets to halt renal disease progression.
6 days back