.webp&w=384&q=75){kind=logo}
Loading, please wait...
Loading, please wait...
The HORIZON trial provided randomized evidence that adding a Hydrus Microstent to cataract surgery can reduce intraocular pressure and medication burden. A five-year post hoc analysis examined visual-field progression, a more patient-important endpoint than pressure alone. The analysis compared eyes undergoing cataract surgery with or without Hydrus implantation and evaluated change in mean deviation over time. The work highlights an important principle in glaucoma care: lowering IOP is valuable because the ultimate goal is to preserve visual function, not simply achieve a laboratory target. The analysis also illustrates the difficulty of using visual-field progression as an endpoint because perimetric variability can obscure small changes over several years. For HCPs, the study supports monitoring both structure and function and interpreting visual-field trends longitudinally rather than from isolated tests. MIGS may be most attractive when it can meaningfully reduce medication burden while maintaining pressure control, particularly during cataract surgery. AIOC's glaucoma programme specifically addresses visual-field interpretation, OCT ganglion-cell assessment and MIGS, making this evidence highly relevant.
Read summarized clinical updates, watch expert medical content, and earn CME certifications right from your smartphone.
Open your smartphone camera to scan and install.
The HORIZON trial provided randomized evidence that adding a Hydrus Microstent to cataract surgery can reduce intraocular pressure and medication burden. A five-year post hoc analysis examined visual-field progression, a more patient-important endpoint than pressure alone. The analysis compared eyes undergoing cataract surgery with or without Hydrus implantation and evaluated change in mean deviation over time. The work highlights an important principle in glaucoma care: lowering IOP is valuable because the ultimate goal is to preserve visual function, not simply achieve a laboratory target. The analysis also illustrates the difficulty of using visual-field progression as an endpoint because perimetric variability can obscure small changes over several years. For HCPs, the study supports monitoring both structure and function and interpreting visual-field trends longitudinally rather than from isolated tests. MIGS may be most attractive when it can meaningfully reduce medication burden while maintaining pressure control, particularly during cataract surgery. AIOC's glaucoma programme specifically addresses visual-field interpretation, OCT ganglion-cell assessment and MIGS, making this evidence highly relevant.
Today
The phase 3 ACACIA-HCM trial reveals that aficamten improves cardiac structure, diastolic relaxation, functional capacity, and symptom burden in symptomatic nonobstructive hypertrophic cardiomyopathy, marking a major milestone in targeted myosin inhibition.
6 days back
A clinical study shows that automated breast ultrasound paired with artificial intelligence accurately classifies BIRADS 3-4 lesions, reaching 95% sensitivity and 79% specificity. This diagnostic advance promises to reduce unnecessary core needle biopsies and refine clinical workflows in breast imaging.
3 weeks back
Researchers have engineered freestanding hierarchical-porous BCZT thin films that resist cracking and enhance ultrasonic energy harvesting in soft tissue. Achieving high piezoelectric output and acoustic matching, this lead-free material offers transformative potential for implantable bioelectronics.
6 days back
A novel pathology-adaptive surface engineering strategy uses functionalized plasma polymer coatings to selectively modulate AGE adsorption, reducing oxidative stress and restoring bone formation in diabetic and aging microenvironments.
3 weeks back
A breakthrough study identifies the Klotho/PKCα/CUX1/SPARC/TGFβ-RII axis as a critical driver of podocyte mitochondrial injury and ferroptosis in diabetic kidney disease, unveiling promising molecular targets to halt renal disease progression.
6 days back
