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In this study of 144 triple-negative breast cancer (TNBC) patients undergoing neoadjuvant therapy, higher skeletal muscle density (SMD) was associated with improved pathologic complete response (pCR) and event-free survival, particularly in those receiving chemoimmunotherapy. CT-derived SMD and PD-L1 combined positive score independently predicted pCR. SMD is a promising predictive biomarker of treatment efficacy in chemoimmunotherapy patients.

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In this study of 144 triple-negative breast cancer (TNBC) patients undergoing neoadjuvant therapy, higher skeletal muscle density (SMD) was associated with improved pathologic complete response (pCR) and event-free survival, particularly in those receiving chemoimmunotherapy. CT-derived SMD and PD-L1 combined positive score independently predicted pCR. SMD is a promising predictive biomarker of treatment efficacy in chemoimmunotherapy patients.
2 months ago

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