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In this retrospective study of 105 patients with HER2-positive metastatic breast cancer, 24 received at least two HER2-targeted tyrosine kinase inhibitor (TKI) regimens. Of these, 58% remained on a subsequent TKI for over six months, and 42% had longer treatment durations on later regimens. These findings support the sequential use of HER2-targeted TKIs as a viable strategy, even after prior TKI exposure.
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In this retrospective study of 105 patients with HER2-positive metastatic breast cancer, 24 received at least two HER2-targeted tyrosine kinase inhibitor (TKI) regimens. Of these, 58% remained on a subsequent TKI for over six months, and 42% had longer treatment durations on later regimens. These findings support the sequential use of HER2-targeted TKIs as a viable strategy, even after prior TKI exposure.
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