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Experts examined 235 breast cancer patients treated with neoadjuvant systemic therapy (NST) followed by breast-conserving surgery (BCS) and found that while "no-ink-on-tumor" margins didn't significantly impact loco-regional free survival (LRFS), margins greater than 1mm were associated with significantly superior 5-year LRFS, as well as longer disease-free survival and overall survival. This suggests a >1mm margin is optimal for these patients.

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Experts examined 235 breast cancer patients treated with neoadjuvant systemic therapy (NST) followed by breast-conserving surgery (BCS) and found that while "no-ink-on-tumor" margins didn't significantly impact loco-regional free survival (LRFS), margins greater than 1mm were associated with significantly superior 5-year LRFS, as well as longer disease-free survival and overall survival. This suggests a >1mm margin is optimal for these patients.
2 months ago

Kenya's confirmation of its eighth Ebola infection highlights the acute risk of secondary transmission in hospital environments. Clinicians must maintain high vigilance, enforce strict infection prevention protocols, and implement rapid triage mechanisms for viral hemorrhagic fevers across healthcare settings.
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Maternal anaemia contributes to nearly half of pregnancy-related fatalities across India. To prevent complications, Uttar Pradesh has added single-dose parenteral iron to its essential medicines list. This clinical transition aims to restore haemoglobin rapidly and protect high-risk mothers across rural facilities.
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India's food safety authority FSSAI has issued show-cause notices to Gemini Edibles, BigBasket, and Flipkart for unpermitted cardiovascular claims regarding Freedom Rice Bran Oil. This regulatory move highlights the strict enforcement of advertising standards and the clinical necessity of evidence-based lipid care.
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The state government is deploying helicopter emergency medical services across the Mumbai-Pune Expressway, Samruddhi Mahamarg, and Mumbai-Goa Highway. This initiative establishes unified standard operating procedures to enable rapid triage, advanced prehospital resuscitation, and seamless trauma care transfers.
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Atherosclerotic cardiovascular disease guidelines often rely on European-derived lipoprotein(a) cutoffs. However, baseline Lp(a) levels vary widely across ancestries, including South Asians and Africans. Clinicians must interpret Lp(a) values within overall absolute cardiovascular risk.
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