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Experts examined 11,470 women with stage I–III early-stage breast cancer and found that adjuvant bone-modifying agent (BMA) use increased modestly following the 2017 ASCO/CCO guideline recommendations. However, overall prescribing remained low, and denosumab was more commonly used than bisphosphonates. BMA use was more likely in postmenopausal patients and those receiving chemotherapy, endocrine therapy, or with bone loss diagnoses.

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Experts examined 11,470 women with stage I–III early-stage breast cancer and found that adjuvant bone-modifying agent (BMA) use increased modestly following the 2017 ASCO/CCO guideline recommendations. However, overall prescribing remained low, and denosumab was more commonly used than bisphosphonates. BMA use was more likely in postmenopausal patients and those receiving chemotherapy, endocrine therapy, or with bone loss diagnoses.
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