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This study of 711 non-metastatic triple-negative breast cancer (TNBC) patients evaluated the impact of neoadjuvant (NACT) versus adjuvant (ACT) chemotherapy timing on overall survival (OS) and event-free survival (EFS). While unadjusted analysis suggested worse OS with NACT, multivariate analysis, especially in advanced-stage disease achieving pathological complete response (pCR), indicated NACT's superiority over ACT.

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This study of 711 non-metastatic triple-negative breast cancer (TNBC) patients evaluated the impact of neoadjuvant (NACT) versus adjuvant (ACT) chemotherapy timing on overall survival (OS) and event-free survival (EFS). While unadjusted analysis suggested worse OS with NACT, multivariate analysis, especially in advanced-stage disease achieving pathological complete response (pCR), indicated NACT's superiority over ACT.
2 months ago

Kenya's confirmation of its eighth Ebola infection highlights the acute risk of secondary transmission in hospital environments. Clinicians must maintain high vigilance, enforce strict infection prevention protocols, and implement rapid triage mechanisms for viral hemorrhagic fevers across healthcare settings.
4 days back

Maternal anaemia contributes to nearly half of pregnancy-related fatalities across India. To prevent complications, Uttar Pradesh has added single-dose parenteral iron to its essential medicines list. This clinical transition aims to restore haemoglobin rapidly and protect high-risk mothers across rural facilities.
Last week

India's food safety authority FSSAI has issued show-cause notices to Gemini Edibles, BigBasket, and Flipkart for unpermitted cardiovascular claims regarding Freedom Rice Bran Oil. This regulatory move highlights the strict enforcement of advertising standards and the clinical necessity of evidence-based lipid care.
6 days back

The state government is deploying helicopter emergency medical services across the Mumbai-Pune Expressway, Samruddhi Mahamarg, and Mumbai-Goa Highway. This initiative establishes unified standard operating procedures to enable rapid triage, advanced prehospital resuscitation, and seamless trauma care transfers.
Last week

Atherosclerotic cardiovascular disease guidelines often rely on European-derived lipoprotein(a) cutoffs. However, baseline Lp(a) levels vary widely across ancestries, including South Asians and Africans. Clinicians must interpret Lp(a) values within overall absolute cardiovascular risk.
Last week