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This meta-analysis of 39 observational studies examined the association between antihypertensive medication (AHTN) use and kidney cancer (KC) risk, independent of hypertension. After adjusting for hypertension, AHTN use was linked to elevated KC risk, particularly with calcium channel blockers (RR: 1.40) and diuretics (RR: 1.36). These findings suggest certain AHTN classes may increase KC risk.

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This meta-analysis of 39 observational studies examined the association between antihypertensive medication (AHTN) use and kidney cancer (KC) risk, independent of hypertension. After adjusting for hypertension, AHTN use was linked to elevated KC risk, particularly with calcium channel blockers (RR: 1.40) and diuretics (RR: 1.36). These findings suggest certain AHTN classes may increase KC risk.
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