An observational study from the NIH All of Us Research Program reveals that adding a multi-ancestry polygenic risk score to machine learning models provides only modest improvements in predicting adult weight gain, underscoring the enduring significance of routine clinical and lifestyle factors.

A study in JAMIA Open shows lightweight open-source reasoning LLMs achieve up to 95% sensitivity and accelerate evidence synthesis screening by nearly twentyfold, presenting a cost-effective, scalable AI solution for biomedical research and systematic reviews.

A landmark study details how an enterprise pediatric remote patient management model expanded from a single cardiology pilot to 16 diverse specialty programs by combining centralized digital operations with specialty clinical leadership.

A comparative review of tension band wiring and intramedullary screw fixation in thumb metacarpophalangeal arthrodesis, evaluating union rates, hardware complications, and clinical outcomes.

A breakthrough ultrathin multimodal sensor decouples physical hemodynamic monitoring from disposable electrochemical calibration, achieving long-term wearable glucose prediction with 81.36% accuracy and a 9.12% MARD. This offers a robust, drift-free solution for outpatient metabolic surveillance.