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The effectiveness & influencing factors of washed microbiota transplantation (WMT) in treating 63 refractory functional constipation (FC)-related therapeutic target cases were investigated. Improvement rates for specific targets were 35%-60.9% at week 24. Overall response rates were 42.9%-50.8%. Clinical remission & improvement rates were 54% & 68.3% at week 4. 22 mild adverse events occurred. Multiple WMT courses enhanced efficacy.

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The effectiveness & influencing factors of washed microbiota transplantation (WMT) in treating 63 refractory functional constipation (FC)-related therapeutic target cases were investigated. Improvement rates for specific targets were 35%-60.9% at week 24. Overall response rates were 42.9%-50.8%. Clinical remission & improvement rates were 54% & 68.3% at week 4. 22 mild adverse events occurred. Multiple WMT courses enhanced efficacy.
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