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A systematic review analyzed 23 studies (n=2648) of clinically diagnosed & 171 pathologically verified cases of Multiple System Atrophy (MSA). The prevalence of cognitive issues, depressive symptoms, sleep disturbances, pain, fatigue & symptoms of autonomic failure in MSA varied widely. The study highlighted the under-recognition of NMS in routine clinical practice and emphasized the need for a holistic approach to care for individuals with MSA.

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A systematic review analyzed 23 studies (n=2648) of clinically diagnosed & 171 pathologically verified cases of Multiple System Atrophy (MSA). The prevalence of cognitive issues, depressive symptoms, sleep disturbances, pain, fatigue & symptoms of autonomic failure in MSA varied widely. The study highlighted the under-recognition of NMS in routine clinical practice and emphasized the need for a holistic approach to care for individuals with MSA.
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