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Experts analyzed LDL-C burden in 112 elderly familial hypercholesterolemia (FH) patients, 49% of whom had coronary heart disease (CHD). Patients with CHD had significantly higher LDL-C burden at ages 45, 50, and 60 years and higher pre-treatment time-weighted average (TWA) LDL-C. Women had higher TWA LDL-C during follow-up. These findings underscore the importance of early LDL-C management to reduce CHD risk in FH patients.
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Experts analyzed LDL-C burden in 112 elderly familial hypercholesterolemia (FH) patients, 49% of whom had coronary heart disease (CHD). Patients with CHD had significantly higher LDL-C burden at ages 45, 50, and 60 years and higher pre-treatment time-weighted average (TWA) LDL-C. Women had higher TWA LDL-C during follow-up. These findings underscore the importance of early LDL-C management to reduce CHD risk in FH patients.
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