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Researchers assessed the association between serum Carbohydrate Antigen 125 (CA125) levels and long-term mortality in 1,413 chronic heart failure (CHF) patients. Elevated CA125 levels were significantly linked to increased all-cause mortality, with the strongest association in HFpEF patients. The ROC analysis showed moderate predictive accuracy. These findings suggest that serum CA125 may serve as a prognostic biomarker for CHF mortality.

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Researchers assessed the association between serum Carbohydrate Antigen 125 (CA125) levels and long-term mortality in 1,413 chronic heart failure (CHF) patients. Elevated CA125 levels were significantly linked to increased all-cause mortality, with the strongest association in HFpEF patients. The ROC analysis showed moderate predictive accuracy. These findings suggest that serum CA125 may serve as a prognostic biomarker for CHF mortality.
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