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This study analyzed 1,152 patients with chronic heart failure (HF) and left ventricular systolic dysfunction to assess sex differences in the prognostic impact of right ventricular dysfunction (RVD). RVD was present in 17% of patients and was associated with worse symptoms, severe LVSD, and higher BNP levels. RVD independently predicted mortality, but this effect was only significant in women, highlighting sex-specific prognostic differences.

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This study analyzed 1,152 patients with chronic heart failure (HF) and left ventricular systolic dysfunction to assess sex differences in the prognostic impact of right ventricular dysfunction (RVD). RVD was present in 17% of patients and was associated with worse symptoms, severe LVSD, and higher BNP levels. RVD independently predicted mortality, but this effect was only significant in women, highlighting sex-specific prognostic differences.
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A premature neonate developed upper limb compartment syndrome after uterine rupture extruded the arm through a scar defect. Conservative management with continuous monitoring yielded complete functional recovery and normal limb growth at 10-year follow-up, highlighting non-operative safety in selected cases.
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Atherosclerosis involves extensive glycometabolic reprogramming across immune and vascular cells. This review examines how glycolysis, the pentose phosphate pathway, and lactate-driven epigenetic shifts fuel plaque vulnerability, while highlighting novel therapeutic targets like PFKFB3 and LDHA.
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