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Researchers examined the link between estrogen-containing oral contraceptive (OCP) use and hypothyroidism in 1001 women. Higher sex hormone-binding globulin (SHBG) levels, a marker of OCP use, were associated with increased odds of hypothyroidism, rising significantly at the 99th percentile. Ethnicity also influenced hypothyroidism risk. Findings suggest SHBG levels may reflect OCP exposure and thyroid dysfunction risk.

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Researchers examined the link between estrogen-containing oral contraceptive (OCP) use and hypothyroidism in 1001 women. Higher sex hormone-binding globulin (SHBG) levels, a marker of OCP use, were associated with increased odds of hypothyroidism, rising significantly at the 99th percentile. Ethnicity also influenced hypothyroidism risk. Findings suggest SHBG levels may reflect OCP exposure and thyroid dysfunction risk.
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