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Experts examined 380 patients with reduced left ventricular ejection fraction (LVEF) found that rest cardiac MRI (CMR) with late gadolinium enhancement (LGE) had a sensitivity of only 57% for detecting significant coronary artery disease (CAD). A CMR-first strategy missed 43% of CAD cases, many needing revascularization. CMR alone is insufficient for identifying CAD in these patients and should be combined with other diagnostic tools.

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Experts examined 380 patients with reduced left ventricular ejection fraction (LVEF) found that rest cardiac MRI (CMR) with late gadolinium enhancement (LGE) had a sensitivity of only 57% for detecting significant coronary artery disease (CAD). A CMR-first strategy missed 43% of CAD cases, many needing revascularization. CMR alone is insufficient for identifying CAD in these patients and should be combined with other diagnostic tools.
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