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A large NHANES cohort study reveals that higher Healthy Eating Index scores significantly reduce all-cause mortality risk in CKD patients by 45%. This analysis highlights the importance of comprehensive diet quality and medical nutrition therapy in renal care to optimize long-term clinical survival.

En bloc kidney HOPE presents an innovative technical workaround in DCD kidney transplantation. By utilizing aortic cannulation and low-pressure hypothermic oxygenated perfusion for 18 hours, this approach preserves graft function, mitigates ischemia-reperfusion injury, and rescues marginal donor organs.

An analysis of 2,597 clinical quiz responses highlights significant diagnostic gaps in identifying rare causes of AA amyloidosis and distinguishing it from AL amyloidosis, underscoring the vital role of case-based digital education for nephrologists and internists.

The von Hippel-Lindau tumor suppressor undergoes dynamic aggregation under microenvironmental stress. This conformational shift supports cancer cell dormancy and drug resistance, revealing novel therapeutic opportunities for chemical chaperones and amyloid inhibitors in modern oncology care.

Managing antimicrobial dosing in critically ill patients with renal dysfunction requires balancing clearance changes with pathogen eradication. Discover how ICU nomograms, therapeutic drug monitoring, and precision dosing guide therapy to prevent toxicity and clinical failure.