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"Wherever the art of Medicine is loved, there is also a love of Humanity."
— Hippocrates

Neonatal cardiac surgery presents severe hemostatic challenges because post-CPB bleeding remains a critical issue for surgical teams. Early detection of coagulopathy is vital to ensure patient safety and improve surgical outcomes. Specifically, implementing ROTEM neonatal cardiac surgery protocols helps guide precise transfusion decisions while minimizing unnecessary exposure to blood products. Consequently, researchers recently conducted a retrospective cohort study involving 58 neonates to compare ROTEM-guided management with conventional strategies. Furthermore, the results showed that the ROTEM group maintained significantly higher postoperative hemoglobin and hematocrit levels after surgery.
During the study, infants in the ROTEM-guided group required fewer transfusions of packed red blood cells and platelet concentrates. Additionally, these patients demonstrated a significantly lower requirement for cryoprecipitate when compared to those in the conventional group. Therefore, point-of-care thromboelastometry proves superior since it provides real-time data for immediate clinical action. Ultimately, integrating these targeted algorithms reduces the overall blood product burden and minimizes potential transfusion-related complications. In addition, this approach effectively modulates transfusion patterns for better recovery.
The routine use of ROTEM as a decision parameter offers a clear advantage over traditional laboratory tests. Since neonates have limited circulating blood volumes, avoiding excessive transfusions is essential to prevent volume overload. Moreover, the study indicates that ROTEM helps clinicians identify specific clotting deficiencies faster than standard monitoring. As a result, neonates receive exactly what they need at the right time. Clearly, adopting these point-of-care protocols marks a significant step toward safer neonatal cardiac interventions.
ROTEM provides rapid, real-time insights into clot strength and stability at the bedside. In contrast, conventional tests often take much longer and may not reflect the complex hemostatic changes occurring during surgery.
Reducing transfusions in neonates is vital because it lowers the risk of transfusion-related lung injury and volume overload. Furthermore, it helps preserve the fragile physiologic balance of a newborn during recovery.
Disclaimer: This content is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition. Refer to the latest local and national guidelines for clinical practice.
References
Saglam S et al. Evaluation of thromboelastometry (Rotem) - guided and conventional hemostasis management effectiveness in neonatal congenital cardiac surgery. Perfusion. 2026 Feb 21. doi: 10.1177/02676591261427684. PMID: 41721642.
Naguib AN, Carrillo SA, Corridore M, et al. A ROTEM-Guided Algorithm Aimed to Reduce Blood Product Utilization During Neonatal and Infant Cardiac Surgery. J Extra Corpor Technol. 2023;55(2):60-69. doi:10.1051/ject/2023017.
Görlinger K, Kammerer T. Value of Point-of-Care Algorithms in Pediatric Cardiac Surgery. J Card Crit Care TSS. 2024;8(3):181-184. doi:10.25259/JCCC_43_2024.

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