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"Wherever the art of Medicine is loved, there is also a love of Humanity."
— Hippocrates

The International Classification of Diseases (ICD-11) now identifies Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD) as two distinct conditions. Consequently, clinicians require precise assessment methods to differentiate between these disorders effectively. A recent study compared the self-report International Trauma Questionnaire (ITQ) with the clinician-administered International Trauma Interview (ITI). The results highlight significant differences in how these ICD-11 PTSD diagnosis tools perform in clinical settings, especially regarding symptom severity reporting.
The study involved 108 veterans who completed both the ITQ and the ITI assessments. Researchers found that patients consistently reported higher symptom levels on the self-report ITQ compared to the clinician’s structured evaluation. Specifically, the ITQ demonstrated excellent sensitivity (0.94) for identifying general trauma-related pathology. However, it showed limited specificity when diagnosing standalone PTSD. This suggests that while the ITQ is an exceptional screening tool, it may lead to over-diagnosis if clinicians use it as the sole diagnostic evidence.
Furthermore, the diagnostic agreement for individual categories like PTSD or CPTSD alone was only fair to moderate. The ITQ’s high sensitivity ensures that healthcare providers miss very few cases during initial intake. Nevertheless, the low positive predictive value (0.39) for standalone PTSD means many patients might be incorrectly flagged for the disorder. Therefore, practitioners in India and elsewhere should use the ITQ primarily as a first-line screen before conducting a thorough, structured clinical interview.
Clinicians must recognize that self-report measures often reflect a patient's broader sense of distress rather than specific diagnostic criteria. In contrast, the International Trauma Interview allows for a nuanced assessment of symptom severity, frequency, and duration. For instance, the ITI can better differentiate between standard PTSD symptoms and the \"Disturbances in Self-Organization\" (DSO) symptoms required for a CPTSD diagnosis. Consequently, the clinician-administered interview remains the gold standard for reaching a definitive diagnosis in complex trauma cases.
No, the ITQ should serve as a screening tool rather than a total replacement. While it captures almost all cases, its tendency to over-report symptoms requires a clinician-led follow-up to ensure diagnostic accuracy and avoid false positives.
ICD-11 PTSD focuses on three symptom clusters: re-experiencing, avoidance, and a persistent sense of threat. CPTSD includes these three clusters plus additional \"Disturbances in Self-Organization\" (DSO), such as affective dysregulation, negative self-concept, and relationship difficulties.
Disclaimer: This content is for informational and educational purposes only. It does not constitute medical advice or a professional relationship. Refer to the latest local and national guidelines for clinical practice.
References
1. Melkevik O et al. Self-reported versus clinician-evaluated symptom assessment and diagnosis of ICD-11 PTSD and CPTSD: a comparison between the International Trauma Interview and the International Trauma Questionnaire. Eur J Psychotraumatol. 2026 Dec undefined. doi: 10.1080/20008066.2026.2635917. PMID: 41853968.
2. Hyland P, et al. Initial Insights into ICD-11 Complex PTSD and Emotional Distress in Emerging Adults in India: Prevalence, Predictors, and Psychosocial Correlates. J Trauma Dissociation. 2025. doi: 10.1080/15299732.2025.2289431.
3. Roberts NP, et al. Validation of the International Trauma Interview (ITI) for the Clinical Assessment of ICD-11 PTSD and CPTSD. Eur J Psychotraumatol. 2019;10(1):1588162.

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