Atopic dermatitis (AD) is a multifactorial disease and represents a wide spectrum of phenotypes. The complex pathophysiology of AD involves both underlying skin barrier abnormalities and immune dysregulation. This CME will not only describe the complex pathogenesis of AD driven by type 2 immunity, microbiome alterations, and impaired epithelial barrier but also give an overview of current diagnosis and future outlooks (machine learning, molecular diagnostics). It will also brief the audience on...